Table 1.

Cα-Cα distance between residues in the framework regions of VH and VL in the scFV(H4) model structure.

Site Pair	Locations	Distance (Å)
H44-L100	FR H2, FR L4	5.36
H46-L98	FR H2, FR L4	6.23
H101-L44	FR H4, FR L2	6.58
H103-L42	FR H4, FR L2	6.98
H103-L43	FR H4, FR L2	5.73