Table 2.
Patient and Disease Characteristics
| Characteristic | No. of Patients (N = 123) | % |
|---|---|---|
| Median age, years | 61 | |
| Sex | ||
| Male | 86 | 70 |
| Female | 37 | 30 |
| Histology | ||
| Adenocarcinoma | 56 | 46 |
| Squamous | 28 | 23 |
| Large cell | 17 | 14 |
| Adenocarcinoma with BAC features/BAC | 5 | 4 |
| Other | 17 | 14 |
| Stage | ||
| IIIB | 18 | 15 |
| IV | 105 | 85 |
| Race | ||
| White | 112 | 91 |
| Black | 3 | 2 |
| Asian | 2 | 1.5 |
| Other | 6 | 5 |
| Smoking status | ||
| Current | 31 | 25 |
| Former | 66 | 54 |
| Never | 25 | 20 |
| Unknown | 1 | < 1 |
| V arm, No. of plasma samples | ||
| Baseline | 55 | 45 |
| Day 8 | 45 | |
| Day 22 | 35 | |
| Day 43 | 31 | |
| CP arm, No. of plasma samples | ||
| Baseline | 32 | 26 |
| Day 8 | 27 | |
| Day 22 | 30 | |
| Day 43 | 23 | |
| VCP arm, No. of plasma samples | ||
| Baseline | 36 | 29 |
| Day 8 | 32 | |
| Day 22 | 29 | |
| Day 43 | 26 |
Abbreviations: BAC, bronchioloalveolar carcinoma; V, vandetanib; CP, carboplatin and paclitaxel; VCP, vandetanib, carboplatin, and paclitaxel.