TABLE 3.
Hormone concentrations at baseline, 3 months, and 12 months.
| Baseline Geometric Mean (95% CI) | 3-month Geometric Mean (95% CI) | % Δ | P* | P** | 12-month Geometric Mean (95% CI) | % Δ | P* | P** | |
|---|---|---|---|---|---|---|---|---|---|
| Testosterone (ng·dL−1) | |||||||||
| Exercisersa | 446 (400, 496) | 462 (420, 507) | 3.6 | 0.42 | 0.93 | 430 (389, 475) | −3.6 | 0.47 | 0.96 |
| Controlsb | 475 (437, 545) | 486 (448, 528) | 2.3 | 0.25 | 463 (420, 511) | −2.5 | 0.53 | ||
| Free testosterone (ng·dL−1) | |||||||||
| Exercisers | 114 (104, 124) | 112 (104, 122) | −1.8 | 0.58 | 0.49 | 106 (97, 115) | −7.0 | 0.08 | 0.61 |
| Controls | 117 (109, 124) | 117 (110, 125) | 0.0 | 0.68 | 112 (103, 121) | −4.3 | 0.29 | ||
| DHT (ng·dL−1) | |||||||||
| Exercisers | 394 (348, 447) | 451 (400, 508) | 14.5 | 0.001 | 0.04 | 428 (382, 479) | 8.6 | 0.07 | 0.03 |
| Controls | 459 (406, 518) | 467 (413, 529) | 1.7 | 0.27 | 445 (393, 503) | −3.1 | 0.18 | ||
| 3α-Diol-G (ng·mL−1) | |||||||||
| Exercisers | 5.65 (4.85, 6.58) | 5.42 (4.72, 6.23) | −4.1 | 0.25 | 0.31 | 5.64 (4.90, 6.49) | −0.2 | 0.97 | 0.63 |
| Controls | 6.27 (5.37, 7.32) | 6.32 (5.45, 7.32) | 0.8 | 0.79 | 6.09 (5.22, 7.10) | −2.9 | 0.36 | ||
| Estradiol (pg·mL−1) | |||||||||
| Exercisers | 32.9 (30.8, 35.1) | 33.0 (31.0, 35.1) | 0.3 | 0.84 | 0.95 | 31.7 (29.5, 34.1) | −3.6 | 0.30 | 0.91 |
| Controls | 35.0 (32.6, 37.5) | 35.1 (32.9, 37.5) | 0.3 | 0.80 | 34.0 (32.1, 36.1) | −2.9 | 0.44 | ||
| Free estradiol (pg·mL−1) | |||||||||
| Exercisers | 0.92 (0.86, 0.99) | 0.90 (0.84, 0.95) | −2.2 | 0.33 | 0.64 | 0.87 (0.81, 0.94) | −5.4 | 0.06 | 0.67 |
| Controls | 0.96 (0.89, 1.03) | 0.95 (0.89, 1.01) | −1.0 | 0.84 | 0.92 (0.87, 0.98) | −4.2 | 0.26 | ||
| SHBG (nM) | |||||||||
| Exercisers | 27.2 (24.5, 30.1) | 31.1 (28.3, 34.1) | 14.3 | < 0.001 | 0.04 | 29.6 (26.8, 32.7) | 8.9 | 0.001 | 0.13 |
| Controls | 30.0 (27.0, 33.4) | 31.7 (28.6, 35.1) | 5.7 | 0.04 | 31.2 (28.2, 34.7) | 4.0 | 0.10 | ||
a
N = 51 exercisers at baseline and 50 exercisers at 3 months and 12 months.
b
N = 51 controls at baseline, 3 months, and 12 months.
*
P value for difference in hormone from baseline to 3 months or from baseline to 12 months within the stated treatment group.
**
P value for difference in hormone change from baseline to 3 months or from baseline to 12 months in exercisers vs controls.