TABLE 4.
Hormone concentrations by change in percent body fat from baseline to 3 months and 12 months.
| Baseline Geometric Mean (95% CI) | 3-month Geometric Mean (95% CI) | % Δ | P* | P** | 12-month Geometric Mean (95% CI) | % Δ | P* | P** | |
|---|---|---|---|---|---|---|---|---|---|
| DHT (ng·dL−1) | |||||||||
| Gained percent body fata | |||||||||
| Exercisers | 379 (289, 497) | 398 (310, 511) | 5.0 | 0.37 | Ref. | 401 (304, 529) | 5.8 | 0.01 | Ref. |
| Controls | 501 (431, 583) | 489 (415, 577) | −2.4 | 468 (391, 561) | −6.6 | ||||
| Lost 0–1.5% body fatb | |||||||||
| Exercisers | 335 (252, 445) | 358 (226, 480) | 6.9 | 0.14 | 0.30 | 348 (263, 459) | 3.9 | 0.28 | 0.68 |
| Controls | 418 (316, 553) | 410 (324, 518) | −1.9 | 402 (317, 510) | −3.8 | ||||
| Lost > 1.5% body fatc | |||||||||
| Exercisers | 424 (360, 500) | 511 (441, 592) | 20.5 | 0.77 | 0.48 | 471 (412, 538) | 11.1 | 0.78 | 0.37 |
| Controls | 425 (339, 533) | 509 (363, 714) | 19.8 | 456 (349, 594) | 7.3 | ||||
| SHBG (nM) | |||||||||
| Gained percent body fata | |||||||||
| Exercisers | 26.0 (20.6, 32.8) | 30.2 (24.7, 398) | 16.2 | 0.06 | Ref. | 27.8 (22.6, 34.0) | 6.9 | 0.22 | Ref. |
| Controls | 30.0 (26.3, 34.4) | 30.8 (26.5, 35.9) | 2.7 | 30.5 (26.3, 35.4) | 1.7 | ||||
| Lost 0–1.5% body fatb | |||||||||
| Exercisers | 21.8 (18.0, 26.4) | 24.8 (20.0, 30.7) | 13.8 | 0.42 | 0.48 | 24.0 (20.1, 28.5) | 10.1 | 0.75 | 0.73 |
| Controls | 29.4 (23.5, 36.8) | 31.4 (26.3, 37.5) | 6.8 | 31.6 (26.4, 37.8) | 2.2 | ||||
| Lost > 1.5% body fatc | |||||||||
| Exercisers | 29.9 (26.1, 34.2) | 34.1 (30.4, 38.3) | 14.0 | 0.77 | 0.11 | 32.8 (28.7, 37.5) | 9.7 | 0.44 | 0.92 |
| Controls | 30.1 (23.0, 29.5) | 34.2 (26.1, 44.8) | 13.6 | 32.0 (23.7, 43.2) | 6.3 | ||||
a
Change in % body fat > 0; N = 10 exercisers and 24 controls (mean (SD) change: 1.49 (1.15)).
b
Change in % body fat = 0–1.5; N = 10 exercisers and 16 controls (mean (SD) change: −0.75 (0.46)).
c
Change in % body fat > 1.5; N = 29 exercisers and 9 controls (mean (SD) change: 1.49–3.99 (2.45)).
*
P value testing the difference in change from baseline to 3 months or 12 months in exercisers vs controls within change in % body fat category.
**
P value testing the difference in change from baseline to 3 months or 12 months in exercisers vs controls, comparing change in % body fat category vs gained % body fat category.