TABLE 5.
Hormone concentrations by change in V̇O2max from baseline to 12 months.
Baseline Geometric Mean (95% CI) | 3-month Geometric Mean (95% CI) | % Δ | P* | P** | 12-month Geometric Mean (95% CI) | % Δ | P* | P** | |
---|---|---|---|---|---|---|---|---|---|
DHT (ng·dL−1) | |||||||||
Control | 459 (406, 518) | 467 (413, 529) | +1.7 | Ref. | N/A | 445 (393, 503) | −3.1 | Ref. | N/A |
Decrease or < 5% increase | 347 (282, 426) | 369 (296, 461) | +6.3 | 0.52 | Ref. | 347 (289, 416) | 0.0 | 0.51 | Ref. |
5–15% increase | 449 (358, 563) | 504 (428, 593) | +12.2 | 0.33 | 0.59 | 491 (409, 591) | +9.4 | 0.33 | 0.49 |
> 15% increase | 372 (303, 456) | 454 (371, 554) | +22.0 | 0.002 | 0.05 | 466 (384, 564) | +25.7 | 0.001 | 0.003 |
P *** = 0.006 | P *** = 0.05 | P *** = 0.001 | P *** = 0.003 | ||||||
SHBG (nM) | |||||||||
Controla | 30.0 (27.0, 33.4) | 31.7 (28.6, 35.1) | +5.7 | Ref. | N/A | 31.2 (28.2, 34.7) | +4.0 | Ref. | N/A |
Decrease or < 5% increaseb | 24.1 (19.4, 29.9) | 27.7 (22.6, 33.9) | +14.9 | 0.17 | Ref. | 26.4 (22.2, 31.5) | +9.5 | 0.27 | Ref. |
5–15% increasec | 32.4 (27.6, 38.1) | 35.0 (30.4, 40.3) | +8.0 | 0.56 | 0.29 | 35.3 (30.0, 41.6) | +9.0 | 0.49 | 0.94 |
> 15% increased | 24.8 (21.7, 28.4) | 29.8 (26.2, 34.0) | +20.2 | 0.002 | 0.47 | 28.9 (25.2, 33.3) | +16.5 | 0.02 | 0.30 |
P *** = 0.01 | P *** = 0.43 | P *** = 0.04 | P *** = 0.28 |
P value testing the difference between change in V̇O2max tertiles and controls from baseline to 12 months vs control group.
P value testing the difference between change in V̇O2max tertiles and the decrease or < 5% increase group, excluding controls.
P value testing a trend across change in V̇O2max tertiles for change from baseline to 12 months.
N = 51.
N = 15.
N = 15.