Table 1.
Features of the reported cases in the literature of splenic abscess due to brucellosis
| Case no. (reference) | Patient’s age (y)/sex | Risk factor | Localization | Brucella antibody titre | Isolate (source) | Therapy | Outcome |
|---|---|---|---|---|---|---|---|
| 1 (8) | 51/M | Farmer | Liver/spleen, bone | 1 : 320 | B.suis (draining sinus from RUQ) | Surgical drainage + Tet | Recovered |
| 2 (8) | 58/M | Butcher | Spleen | 1 : 320 | B. suis (spleen) | Splenectomy + Tet × 3 m | Recovered |
| 3 (8) | 54/M | Cattle | buyer Liver/spleen, lymph node | 1 : 80 | B.suis (draining sinus from LUQ) | Not specified (NS) | Died of hemorrhage from esophageal varices |
| 4 (8) | 53/M | Farmer | Spleen | 1 : 1280 | B. suis (spleen) | Splenectomy + Tet | Recovered |
| 5 (8) | 53/M | Farmer | Spleen | 1 : 1280 | None | Splenectomy + antibiotic (NS) | Recovered |
| 6 (5) | 3/M | Unknown | Liver/spleen | 1 : 1280 | B. melitensis (Liver, bone marrow) | Percutaneous drainage of liver abscess + Rif and TMP-SMZ × 2 m | Recovered |
| 7 (3) | 53/M | Past history of brucellosis | Spleen | 1 : 80 | Negative | 2 cycles of Doxy × 2 m and inj. Strepto × 21 d | Relapsed |
| 8 (3) | 80/NS | Past history of brucellosis | Spleen | 1 : 320 | Negative | Doxy × 2 m, inj. Strepto × 21 d + splenectomy followed by Doxy, Rif × 3 m | Died due to causes unrelated to brucellosis |
| 9 (3) | 72/NS | Past history of brucellosis | Spleen | 1 : 40 | Negative | Doxy × 2 m, inj. Strepto × 21 d + splenectomy followed by Doxy, Rif × 3 m | Recovered |
| 10 (2) | 70/F | Consumption of unpasteurized milk products | Spleen | 1 : 320 | B. melitensis (Blood) | Doxy, Rif × 6 weeks, inj. Strepto × 21 d | Recovered |
| 11 (9) | 19/M | Contact with dairy products | Spleen, aortic valve | High titres of SAT | B. melitensis (Blood, spleen, vegetations) | Splenectomy + antibiotics (NS) | Recovered |
| 12 (4) | 61/M | Unknown | Spleen | 1 : 1280 | Negative | Rif, Doxy and TMP-SMZ | Recovered |
| 13 (7) | 45/M | Livestock industry worker | Spleen, aortic valve | 1 : 160 | B. abortus (Blood) | Genta and Rif, Doxy, TMP-SMZ × 12 m | Recovered |
| 14 (PR) | 8/M | Consumption of raw goat’s milk | Spleen | 1 : 640 | B. melitensis (Blood, splenic aspirate) | Doxy × 6 weeks Inj. Strepto × 2 weeks | Recovered |
NOTE: RUQ – right upper quadrant; Tet – tetracycline; m – months; LUQ – left upper quadrant; NS – not specified; Rif – rifampicin; TMP-SMZ – trimethoprimsulfamethoxazole; Doxy – doxycycline; Strepto – streptomycin; d – days; Genta – gentamicin; PR – present report