Logarithmic-scale plots of
normalized spot intensities (arbitrary units). Spot intensities
were normalized after subtracting their backgrounds, i.e. the average
spot intensities of 12 mammal gene spots. After substituting the
intensities of less than 10 with that of 10, which was less than
the standard deviations of their backgrounds, the intensities were
plotted logarithmically. The correlation coefficient is indicated
by r. (A) RNA of strain 1A250 (wild-type) grown
with glucose was used for both Cy3 and Cy5 cDNA-labeling. After
hybridization of microarrays with the Cy3 and Cy5 probes, the respective
spot intensities for 4100 genes, calculated as above, were plotted.
The backgrounds for Cy3 and Cy5 spot intensities were 244.6 ± 42.7 and 278.2 ± 74.4, respectively. (B) RNA of strain 1A250 (wild-type)
grown with and without glucose (Glc) was used for Cy3- and Cy5-labeling,
respectively. The backgrounds for Cy3 and Cy5 spot intensities were
189.3 ± 30.4 and 249.5 ± 46.7,
respectively. (C) RNA of strain 147 (ccpA1)
grown with and without glucose was used for Cy3- and Cy5-labeling,
respectively. The backgrounds for Cy3 and Cy5 spot intensities were
186.3 ± 21.5 and 206.7 ± 31.4,
respectively.