Table 4.
GO-term enrichment of genes over-expressed in the African population
| ID | Ontology | Term | P-value |
|---|---|---|---|
| GO:0004558 | MF | Alpha-glucosidase activity | 0.006 |
| GO:0004806 | MF | Triglyceride lipase activity | 0.021 |
| GO:0003697 | MF | Single-stranded DNA binding | 0.021 |
| GO:0019201 | MF | Nucleotide kinase activity | 0.021 |
| GO:0004129 | MF | Cytochrome-c oxidase activity | 0.036 |
| GO:0019318 | BP | Hexose metabolic process | 0.005 |
| GO:0009586 | BP | Rhodopsin mediated phototransduction | 0.006 |
| GO:0048814 | BP | Regulation of dendrite morphogenesis | 0.009 |
| GO:0014866 | BP | Skeletal myofibril assembly | 0.015 |
| GO:0048139 | BP | Female germ-line cyst encapsulation | 0.015 |
| GO:0035075 | BP | Response to ecdysone | 0.025 |
| GO:0006119 | BP | Oxidative phosphorylation | 0.028 |
| GO:0012502 | BP | Induction of programmed cell death | 0.032 |
| GO:0006631 | BP | Fatty acid metabolic process | 0.035 |
| GO:0007015 | BP | Actin filament organization | 0.035 |
| GO:0030713 | BP | Ovarian follicle cell stalk formation | 0.036 |
| GO:0016028 | CC | Rhabdomere | 0.018 |
| GO:0044429 | CC | Mitochondrial part | 0.025 |
| GO:0016459 | CC | Myosin complex | 0.025 |
| GO:0030425 | CC | Dendrite | 0.035 |
In cases where multiple, related terms within a GO hierarchy were significant, only a single term is given. The complete list is provided in Additional file 3. Ontology abbreviations are: MF, molecular function; BP, biological process; CC, cellular compartment. P-values were determined by a hypergeometric test with Benjamini-Hochberg multiple-test correction.