Table 1.
Pituitary adenoma | Meningioma | |
---|---|---|
PTV definitions | ||
PTV = CTV + 1 mm (CTV = GTV), | PTV = CTV + 1 mm (CTV = GTV) | |
PTV = CTV + 2 - 4 mm (CTV = GTV) | PTV = CTV + 2 - 3 mm (CTV = GTV) | |
Prescribed dose | ||
SRS | 15 - 20 Gy marginal dose, 25 Gy or more for secreting pituitary adenoma | 11 - 18 Gy marginal dose (recommended for 14 Gy or more) |
Conventional fractionated SRT | isocenter 45 - 68 Gy/daily 1.8 Gy/fr., D95 50 - 56 Gy/daily 2 Gy/fr. | |
SRT | 45 - 50 Gy/25 - 28 fr. | 2 Gy/fr. |
Constrains for organs at risk[11] | ||
SRS | Optic tract < 8 - 10 Gy, | |
Conventional fractionated | ||
SRT | Optic tract 50 Gy/25 fr | |
Spinal cord < 50 Gy (10 cm or less in length) | ||
Retina < 45 Gy | ||
Lens < 10 Gy | ||
Brain stem < 60 Gy (1/3 volume) |
SRS; stereotactic radiosurgery, SRT; stereotactic radiotherapy,
GTV; gross tumor volume, CTV; clinical treatment volume, PTV; planning target volume, fr.; fraction,
D95; irradiation dose that included 95% volume of PTV