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. 2011 Jan 27;6:10. doi: 10.1186/1748-717X-6-10

Table 1.

Reference for planning of pituitary adenoma and meningioma

Pituitary adenoma Meningioma
PTV definitions
PTV = CTV + 1 mm (CTV = GTV), PTV = CTV + 1 mm (CTV = GTV)
PTV = CTV + 2 - 4 mm (CTV = GTV) PTV = CTV + 2 - 3 mm (CTV = GTV)
Prescribed dose
SRS 15 - 20 Gy marginal dose, 25 Gy or more for secreting pituitary adenoma 11 - 18 Gy marginal dose (recommended for 14 Gy or more)
Conventional fractionated SRT isocenter 45 - 68 Gy/daily 1.8 Gy/fr., D95 50 - 56 Gy/daily 2 Gy/fr.
SRT 45 - 50 Gy/25 - 28 fr. 2 Gy/fr.
Constrains for organs at risk[11]
SRS Optic tract < 8 - 10 Gy,
Conventional fractionated
SRT Optic tract 50 Gy/25 fr
Spinal cord < 50 Gy (10 cm or less in length)
Retina < 45 Gy
Lens < 10 Gy
Brain stem < 60 Gy (1/3 volume)

SRS; stereotactic radiosurgery, SRT; stereotactic radiotherapy,

GTV; gross tumor volume, CTV; clinical treatment volume, PTV; planning target volume, fr.; fraction,

D95; irradiation dose that included 95% volume of PTV