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. 2011 Feb 16;6(2):e14699. doi: 10.1371/journal.pone.0014699

Table 3. Laboratory features at enrollment visit associated with survival in SCA patients.

Clinical features Survived(n = 1,430; 94.3%) Died(n = 86; 5.7%) Odds Ratio(95% CI) p
n n (%) or mean (SD) n n (%) or mean (SD)
Age at enrollment (years) 1,430 9.5 (7.8) 86 10.2 (8.6) 1.01 (0.98–1.04) 0.408
White blood cell count (x109/L) 1,307 15.9 (6.9) 78 15.7 (7.3) 0.99 (0.96–1.03) 0.849
Hemoglobin (g/dL) 1,306 7.6 (1.3) 79 6.9 (1.6) 0.73 (0.62–0.86) <0.001
Mean Corpuscular volume (fL) 1,298 79.2 (9.5) 77 79.5 (10.9) 1.00 (0.98–1.03) 0.752
Reticulocyte (% of RBC) 832 12.6 (7.1) 33 13.1 (8.6) 1.01 (0.96–1.06) 0.670
Hemoglobin F (%) 1,297 6.3 (4.7) 63 6.6 (4.9) 1.02 (0.96–1.07) 0.575
Total Bilirubin (µmol/L) 1,263 69.7 (56.7) 79 87.5 (81.4) 1.00 (1.00–1.01) 0.010
Direct Bilirubin (µmol/L) 1,157 20.9 (34.2) 72 33.1 (57.6) 1.00 (1.00–1.01) 0.019
Indirect Bilirubin (µmol/L) 1,140 51.5 (53.6) 71 57.1 (60.4) 1.01 (0.99–1.01) 0.396
Lactate dehydrogenase (IU/L) 559 965.4 (483.7) 27 1,103.7 (339.3) 1.00 (0.99–1.00) 0.143
Aspartate transaminase (IU/L) 1,307 50.1 (28.4) 81 49.3 (24.1) 0.99 (0.99–1.01) 0.802
Alkaline phosphatase (IU/L) 1,310 265.6 (124.2) 81 276.7 (152.8) 1.00 (0.99–1.00) 0.442

Association between mortality and laboratory measurements at enrollment was explored using logistic regression.