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. 2011 Feb 16;6(2):e16957. doi: 10.1371/journal.pone.0016957

Table 9. Octadecanoid oxylipins (nM) detected by UPLC (−)ESI-MS/MS in human plasma.

Parent Lipid Classa HMDB ID Common Abbreviaton HM Replicate Plasma (n = 3) Pennington Plasma (n = 70)
C18:2n6 Diol HMDB04705 12,13-DiHOME 7.69±0.59 5.82±3
C18:2n6 Diol HMDB04704 9,10-DiHOME 60.5±3.8 29.7±11
C18:2n6 Epox HMDB04702 12(13)-EpOME 4.88±0.34 7.21±8.8
C18:2n6 Epox HMDB04701 9(10)-EpOME 2.17±0.23 5.47±7.4
C18:2n6 R-OH HMDB04667 13-HODE 47.3±0.53 58.2±28
C18:2n6 R-OH HMDB10223 9-HODE 11.7±0.23 11±6.1
C18:2n6 R-OOH HMDB03871 13-HpODE ND 6.01±5.5
C18:2n6 R-OOH HMDB06940 9-HpODE ND 5.14±3.8
C18:2n6 Epox,R = O HMDB13623 12(13)Ep-9-KODE 3.02±0.27 3.96±2.4
C18:2n6 R = O HMDB04668 13-KODE 4.82±0.68 1.7±1.2
C18:2n6 R = O HMDB04669 9-KODE 2.41±0.29 5.3±2.7
C18:2n6 Triol HMDB04708 9,12,13-TriHOME 0.827±0.21 4.11±2.2
C18:2n6 Triol HMDB04710 9,10,13-TriHOME 0.513±0.083 1.16±0.64
C18:3n3 Diol HMDB10208 15,16-DiHODE 14.5±1 5.93±2.4
C18:3n3 Diol HMDB10201 12,13-DiHODE <0.2 0.219±0.12
C18:3n3 Diol HMDB10221 9,10-DiHODE 2.36±0.15 0.114±0.085
C18:3n3 Epox HMDB10206 15(16)-EpODE 3.27±0.23 2.77±2.1
C18:3n3 Epox HMDB10200 12(13)-EpODE 0.416±0.08 0.468±0.67
C18:3n3 Epox HMDB10220 9(10)-EpODE 2.08±0.075 1.65±2.3
C18:3n3 R-OH HMDB10203 13-HOTE 1.9±0.21 1.11±0.74
C18:3n3 R-OH HMDB10224 9-HOTE 1.98±0.12 1.19±0.91

Class: R-OH - hydroxy fatty acid; R = O - keto fatty acid; Diol - dihydroxy fatty acid; Triol - trihydroxy fatty acid; Epox - epoxy fatty acid; LT - leukotriene; PG - prostaglandin.