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Substrate specificity of PaMTIP.
| Substrate | kcat (s−1) | Km or Ki (µM) | kcat/Km (M−1s−1) |
|---|---|---|---|
| MTI | 4.8 ± 0.2 | 2.6 ± 0.4 | (1.8 ± 0.3) × 106 |
| MTA a | N/A | 70 ± 20 | N/A |
| inosine | 0.57 ± 0.04 | 90 ± 20 | (6 ± 1) × 103[300] b |
| adenosine | 0.0549 ± 0.0005 | 23 ± 1 | (2.4 ± 0.1) × 103[750] b |
MTA is not a substrate of PaMTIP. Ki is used instead of Km for MTA.
Numbers in [] are fold decreases of kcat/Km in comparion with those of MTI.
Values are ± S.E.
