Table 3.
Univariate and multivariate analyses for the long-term combined endpoint (death/re-MI)
| Crude hazard ratio and 95% CI | Multivariate adjusted hazard ratio and 95% CI | P value | |
|---|---|---|---|
| Off-site centre | 1.2 (0.53–2.6) | 1.3 (0.56–3.2) | 0.51 |
| Age (years) | 1.03 (0.99–1.06) | 1.03 (0.99–1.1) | 0.14 |
| Men | 1.0 (0.42–2.4) | – | |
| Diabetes mellitus | 3.2 (0.97–11) | 2.5 (0.63–9.7) | 0.20 |
| Smoker | 1.3 (0.72–2.2) | 1.3 (0.74–2.3) | 0.36 |
| Hypertension | 1.3 (0.54–2.9) | – | |
| Family history of CVD | 0.60 (0.26–1.4) | 0.76 (0.31–1.8) | 0.54 |
| Previous PCI | 0.05 (0–600) | – | |
| Previous CABG | 1.1 (0.15–8.3) | – | |
| Killip class >1 | 2.8 (0.38–21) | 25.1 (2.0–315) | 0.013 |
| Summed ST deviation (mm) | 1.03 (0.72–1.5) | – | |
| Anterior myocardial infarction | 1.3 (0.60–2.9) | 1.4 (0.49–4.0) | 0.54 |
| Q wave | 3.1 (1.2–8.4) | 3.4 (1.02–11.2) | 0.046 |
| Multi-vessel disease (>1) | 1.1 (0.49–2.4) | – | |
| TIMI flow pre PCI <2 | 1.2 (0.51–2.8) | – | |
| TIMI flow post PCI <2 | 0.46 (0.06–3.4) | 0.75 (0.08–7.3) | 0.80 |
| Symptoms-to-admission (h) | 1.06 (0.96–1.16) | 0.94 (0.61–1.5) | 0.79 |
| Door-to-balloon (h) | 1.01 (0.68–1.5) | – | |
| Time-to-treatment (h) | 1.05 (0.96–1.15) | 1.09 (0.71–1.7) | 0.69 |
| LVESV (10 ml) | 1.02 (0.90–1.2) | – | |
| LVEDV (10 ml) | 1.01 (0.91–1.1) | – | |
| LVEF (%) | 1.0 (0.97–1.03) | – | |
| Infarct extent (%) | 1.02 (0.99–1.04) | 1.0 (0.82–1.2) | 0.97 |
| SRS | 1.02 (0.99–1.05) | 1.03 (0.80–1.3) | 0.83 |
| SMS | 1.01 (0.99–1.03) | 1.03 (0.95–1.1) | 0.50 |
| STS | 1.01 (0.99–1.03) | 0.95 (0.86–1.1) | 0.35 |
Variables with a p value <0.5 in univariate analysis and all scintigraphic variables were included in the multivariable model
MI myocardial infarction, LVESV left ventricular end-systolic volume, LVEDV left ventricular end-diastolic volume, LVEF left ventricular ejection fraction, SRS summed rest score, SMS summed motion score, STS summed thickening score