Skip to main content
. Author manuscript; available in PMC: 2012 Feb 15.
Published in final edited form as: Cancer Cell. 2011 Feb 15;19(2):177–191. doi: 10.1016/j.ccr.2010.12.023

Figure 2. Histological analysis of Ptch1+/−;p53−/− eRMS for each Cre line.

Figure 2

Genotypes are indicated in column headings. A tumor from a mouse with germline deletion of the Ptch1 gene is shown as a typical case of eRMS (left column). H&E staining, Masson s trichrome, and immunohistochemical staining for Myogenin and Desmin were performed for diagnosis of all tumors. Arrowheads point to eosinophilic strap-like epithelioid rhabdomyoblasts in H&E panels. Cross striations are shown on trichrome (some cases; arrowheads). Scale bar, 40 μm.