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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Mol Cell Neurosci. 2010 Dec 29;46(2):548–561. doi: 10.1016/j.mcn.2010.12.012

Figure 4. Expression patterns of genes with different profiles are expressed in distinct cell types.

Figure 4

RNA in situ hybridizations of coronal sections of the OB at E15 and E18 along with time course expression data for selected genes. (A–C) E15 OB in situs using probes to the neural progenitor markers Vim, and pax6; and the proliferation marker Ki67. All three markers label the germinal region of the OB. Vim and Ki67 also label the nerve layer which is a common pattern for probes that label the germinal region. (D–F) E15 OB in situ hybridizations for the TF genes Nr2f1, Fox01, and Heyl. These probes specifically label the nerve layer. (G–I) OB in situ hybridizations for the TF genes Mafb, Stmn2 and Id2 performed at E15 and E18. At E15 the genes exhibited a diffuse ring of expression in the OB; at E18, labeled cells could be identified as mitral cells. ONL: olfactory nerve layer. GZ: germinal zone. MCL: mitral cell layer. Bar = 200 µm. For microarray expression plots, units for the X-axis are time, log2ratio values are plotted on the left Y axis, A values on the right. (see Materials and Methods).