Table 1. Classes of TFs encoded by differentially expressed genes.
TFs encoded by genes in differentially expressed genes matched to Interpro domain descriptions. Domains are tabulated by the number of genes in clusters 6–9, number in clusters 2–3, and overall number in the dataset. Many transcription factors contain more than one domain and therefore are included in more than one class.
| Transcription Factor Class | Number Overall | Clusters 6–9 | Clusters 2–3 |
|---|---|---|---|
| Total TFs | 507 | 320 | 135 |
| Znf | 120 | 73 | 34 |
| Pro rich | 60 | 28 | 21 |
| Homeobox | 41 | 28 | 7 |
| HLH | 33 | 16 | 14 |
| HMG | 22 | 19 | 3 |
| ANK | 21 | 11 | 8 |
| Antifreeze | 18 | 13 | 3 |
| AAA ATPase | 13 | 13 | 0 |
| bZip | 12 | 2 | 5 |
| BTB/POZ | 12 | 5 | 4 |
| POU | 12 | 9 | 1 |
| Nuclear receptor | 10 | 1 | 5 |
| RNA Pol | 9 | 7 | 2 |
| WD40 | 7 | 5 | 2 |
| MCM | 7 | 7 | 0 |
| p53_like_TF_DNA-bd | 7 | 4 | 1 |
| Forkhead | 6 | 1 | 1 |
| PAS | 6 | 0 | 6 |
| E2F | 5 | 5 | 0 |
| Ets | 5 | 2 | 1 |
| Chromodomain | 5 | 4 | 1 |
| EF Hand | 4 | 1 | 1 |
| No Match | 102 | ||