Figure 6. CD14 and LBP enhanced meningococcal CPS bioactivity.
Dose-dependent IL-8 release from HEK/TLR2–6 stably transfected cells induced with serogroup B CPS-lpxA in serum-free (SF) or 10% FBS conditions, with or without exogenous rCD14 or rLBP added at 20 ng/ml. The results are representative of two independent experiments.