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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Appl Immunohistochem Mol Morphol. 2011 Jan;19(1):62–69. doi: 10.1097/PAI.0b013e3181ed47bc

Figure 2. Continuous quantitative assessment of Cyclin D1 expression in MCL and control cases represented on a tissue microarray by AQUA.

Figure 2

Mean immunofluorescence within the B-cell mask of duplicate tissue cores from MCL and non-MCL lymphoid tissues stained with anti-Cyclin D1 antibody expressed as AQUA scores. Unpaired t-test shows MCL cases have a significantly higher mean expression of Cyclin D1 compared to non-MCL cases (p = 0.00019). Chromagenic staining of corresponding cases are shown for comparison. FL indicates follicular lymphoma; SLL, small lymphocytic lymphoma; FH, follicular hyperplasia.