Table 2.
Adjusted log cortisol values at wake up and mean differences in log cortisol per hour for different portions of the cortisol curve by tertiles of cynical hostility, the Multiethnic Study of Atherosclerosis (MESA) Stress Study, 2004–2006
| Model 1 | Model 2 | Model 3 | Model 4 | |
|---|---|---|---|---|
| Estimate (std err) | Estimate (std err) | Estimate (std err) | Estimate (std err) | |
| Wake-up value (top tertile of cynical hostility) | 2.36 (0.03) | 2.39 (0.03) | 2.38 (0.04) | 2.4 (0.04) |
| Wake-up value (middle tertile of cynical hostility) | 2.41 (0.04) | 2.42 (0.04) | 2.41 (0.03) | 2.43 (0.04) |
| Wake-up value (lowest tertile of cynical hostility) | 2.44 (0.03) | 2.41 (0.03) | 2.38 (0.03) | 2.39 (0.04) |
| Intercept difference for intertertile difference in cynical hostility | −0.08 (0.04) | −0.02 (0.05) | 0 (0.05) | 0 (0.05) |
| p for intertertile difference | .08 | .66 | .97 | .93 |
| Phase 1 slope* (top tertile of cynical hostility) | 1.96 (0.26) | 2.00 (0.26) | 2.03 (0.27) | 1.8 (0.34) |
| Phase 1 slope (middle tertile of cynical hostility) | 2.04 (0.26) | 2.07 (0.26) | 2.09 (0.28) | 1.87 (0.34) |
| Phase 1 slope lowest tertile of cynical hostility) | 2.04 (0.25) | 2.06 (0.25) | 2.09 (0.28) | 1.87 (0.34) |
| Phase1 slope difference for intertertile difference in cynical hostility | −0.09 (0.07) | −0.06 (0.08) | −0.06 (0.08) | −0.07 (0.08) |
| p for intertertile difference | .25 | .40 | .46 | .40 |
| Phase 2 slope* (top tertile of cynical hostility) | −0.40 (0.09) | −0.45 (0.09) | −0.39 (0.09) | −0.57 (0.11) |
| Phase 2 slope (middle tertile of cynical hostility) | −0.45 (0.08) | −0.49 (0.09) | −0.43 (0.09) | −0.61 (0.11) |
| Phase 2 slope lowest tertile of cynical hostility) | −0.49 (0.09) | −0.51 (0.09) | −0.45 (0.09) | −0.63 (0.11) |
| Phase 2 slope difference for intertertile difference in cynical hostility | 0.09 (0.02) | 0.06 (0.03) | 0.06 (0.03) | 0.06 (0.03) |
| p for intertertile difference | .0004 | .0136 | .0496 | .0461 |
| Phase 3 slope* (top tertile of cynical hostility) | −0.14 (0.01) | −0.13 (0.01) | −0.13 (0.02) | −0.13 (0.02) |
| Phase 3 slope (middle tertile of cynical hostility) | −0.13 (0.01) | −0.13 (0.01) | −0.12 (0.02) | −0.13 (0.02) |
| Phase 3 slope lowest tertile of cynical hostility) | −0.13 (0.01) | −0.13 (0.01) | −0.12 (0.02) | −0.13 (0.02) |
| Phase 3 slope difference for intertertile difference in cynical hostility | −0.01 (0) | 0 (0) | 0 (0) | 0 (0) |
| p for intertertile difference | .07 | .63 | .76 | .69 |
All models adjust for day of collection and wakeup time; in addition, models include other adjustment variables as follows:
Model 1: age+sex; Model 2: Model 1+ race/ethnicity; Model 3: Model 2 + socioeconomic position; Model 4: Model 3 + BMI + smoking.
Estimates are computed at the median or mean level of all covariates. Phases 1, 2 and 3 correspond to time periods 0–30 minutes, 30–120 minutes, and >120 minutes past waking.