Table 1.
Baseline characteristics of frail and non frail participants
| Parameter | Frail (n= 14) | Non frail (n= 17) | P value |
|---|---|---|---|
| Age (years) | 80.4 ± 6.4 | 74.2 ± 6.5 | <0.05 |
| Gender (male/female) | 12/2 | 14/3 | NS |
| Charlson Co-morbidity Score | 3.1 ± 1.9 | 2.4 ± 1.9 | NS |
| Number of medications | 4.6 ± 2.0 | 2.1 ± 1.8 | 0.001 |
| Number of renal disease risk factors | 1.35 ± 1.06 | 1.57 ± 0.94 | NS |
| Height (cm) | 165.1 ± 8.6 | 171.2 ± 7.4 | <0.05 |
| Actual bodyweight (kg) | 77.1 ± 11.7 | 76.8 ± 10.8 | NS |
| Ideal bodyweight (kg) | 62.0 ± 6.5 | 66.4 ± 7.9 | NS |
| Lean bodyweight (kg) | 54.6 ± 8.8 | 55.8 ± 8.4 | NS |
| SCr (mg dl−1) | 1.1 ± 0.1 | 1.0 ± 0.3 | NS |
| CGABW (ml min−1) | 56.7 ± 16.0 | 68.4 ± 15.9 | NS |
| CGIBW (ml min−1) | 45.7 ± 10.9 | 59.4 ± 13.8 | <0.01 |
| CGLBW (ml min−1) | 40.8 ± 10.7 | 51.0 ± 11.5 | <0.05 |
| eGFR (ml min−1) | 65.8 ± 14.4 | 76.8 ± 17.9 | NS |
All values except gender are quoted in mean ± standard deviation (SD); CGABW, Cockcroft Gault estimate of creatinine clearance calculated using actual bodyweight; CGIBW, Cockcroft Gault estimate of creatinine clearance calculated using ideal bodyweight; CGLBW, Cockcroft Gault estimate of creatinine clearance calculated using lean bodyweight; eGFR, estimated glomerular filtration rate calculated using the Modified Diet in Renal Disease equation normalized for body surface area (ml min−1); NS, not significant; SCr, serum creatinine.