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. Author manuscript; available in PMC: 2011 Feb 17.
Published in final edited form as: Pediatrics. 2010 Nov 22;126(6):e1477–e1484. doi: 10.1542/peds.2010-1138

TABLE 3.

Acute Illnesses and Viral Pathogens That Accompanied First Seizure, According to Study Group

Febrile (N = 78) Nonfebrile Illness (N = 34) P
Acute illness type, n (%)
 Acute diarrheal illness 22 (28) 16 (47) .05
 Acute upper respiratory illness 25 (32) 3 (9) .009
Stool specimen results
 Rotavirus, n/N (%) 6/65 (9) 7/25 (28) .02
 Rotavirus genotype
  G1P[8] 3 5
  G3P[8] 2 0
  G9P[8] 1 0
  Unknowna 0 2
 Norovirus, n/N (%) 8/64 (13) 7/23 (30) .05
 Norovirus type
  GI 1 (2) 0 .55
  GII 7 (11) 7 (30) .03
 Enterovirus, n/N (%) 11/43 (26) 0/12 .05
 Parechovirus, n/N (%) 1/43 (2) 0/12 .59
 Adenovirus, n/N (%) 13/43 (30) 1/12 (8) .12
 Bocavirus, n/N (%) 3/43 (7) 1/12 (8) .87
 Multiple infections, n
  Rotavirus/parechovirus 1 0
  Rotavirus/bocavirus 0 1
  Enterovirus/adenovirus 2 0
  Norovirus/adenovirus 0 1
  Norovirus/enterovirus/adenovirus 1 0
  Norovirus/enterovirus/adenovirus/bocavirus 1 0
Serum specimen results, n/N (%)
 Rotavirus 1/6 (17) 0/12 (0) .33
 Norovirus 0/6 (0) 0/12 (0)
CSF specimen results, n/N (%)
 Rotavirus 0/3 (0) 1/2 (50) .40
 Norovirus 0/3 (0) 0/2 (0)

Five children in the unprovoked seizure enrollment group did not have accompanying illness symptoms, by definition. n/N indicates number of children with a positive result per number of children with test performed.

a

Three rotavirus tests were performed clinically without sample available for detailed genotype testing. Results for 2 of these samples were positive; both samples were from children in the nonfebrile-illness group.