TABLE 3.
Acute Illnesses and Viral Pathogens That Accompanied First Seizure, According to Study Group
| Febrile (N = 78) | Nonfebrile Illness (N = 34) | P | |
|---|---|---|---|
| Acute illness type, n (%) | |||
| Acute diarrheal illness | 22 (28) | 16 (47) | .05 |
| Acute upper respiratory illness | 25 (32) | 3 (9) | .009 |
| Stool specimen results | |||
| Rotavirus, n/N (%) | 6/65 (9) | 7/25 (28) | .02 |
| Rotavirus genotype | |||
| G1P[8] | 3 | 5 | |
| G3P[8] | 2 | 0 | |
| G9P[8] | 1 | 0 | |
| Unknowna | 0 | 2 | |
| Norovirus, n/N (%) | 8/64 (13) | 7/23 (30) | .05 |
| Norovirus type | |||
| GI | 1 (2) | 0 | .55 |
| GII | 7 (11) | 7 (30) | .03 |
| Enterovirus, n/N (%) | 11/43 (26) | 0/12 | .05 |
| Parechovirus, n/N (%) | 1/43 (2) | 0/12 | .59 |
| Adenovirus, n/N (%) | 13/43 (30) | 1/12 (8) | .12 |
| Bocavirus, n/N (%) | 3/43 (7) | 1/12 (8) | .87 |
| Multiple infections, n | |||
| Rotavirus/parechovirus | 1 | 0 | |
| Rotavirus/bocavirus | 0 | 1 | |
| Enterovirus/adenovirus | 2 | 0 | |
| Norovirus/adenovirus | 0 | 1 | |
| Norovirus/enterovirus/adenovirus | 1 | 0 | |
| Norovirus/enterovirus/adenovirus/bocavirus | 1 | 0 | |
| Serum specimen results, n/N (%) | |||
| Rotavirus | 1/6 (17) | 0/12 (0) | .33 |
| Norovirus | 0/6 (0) | 0/12 (0) | — |
| CSF specimen results, n/N (%) | |||
| Rotavirus | 0/3 (0) | 1/2 (50) | .40 |
| Norovirus | 0/3 (0) | 0/2 (0) | — |
Five children in the unprovoked seizure enrollment group did not have accompanying illness symptoms, by definition. n/N indicates number of children with a positive result per number of children with test performed.
a
Three rotavirus tests were performed clinically without sample available for detailed genotype testing. Results for 2 of these samples were positive; both samples were from children in the nonfebrile-illness group.