Table 5.
Family room dust: percent difference in microbial biomarkers associated with predictors (home characteristics, demographics, and allergen levels) in multiple regression models (95% confidence interval for percent difference).a
| Characteristic and model | GNB |
GPB |
Fungi |
|||
|---|---|---|---|---|---|---|
| Recombinant factor C | LAL | Midchain 3–OHFAs | Muramic acid | Ergosterol | β-d-Glucan | |
| Multiple regression models with questionnaire predictors | ||||||
| Dampness | ||||||
| Water/mold | 65.6 (23.8 to 113.5)* | 43.8 (20.5 to 71.5)* | — | 5.6 (−4.4 to 16.7) | 18.6 (−0.1 to 40.8) | 9.4 (−5.2 to 26.2) |
| Central air | −28.2 (−44.7 to −3.4)* | −16.2 (−30.1 to 0.4) | — | −14.2 (−22.5 to −4.8)* | — | — |
| Apartment | 10.8 (−41.2 to 107.9) | −15.0 (−43.5 to 27.9) | −15.1 (−30.5 to 3.7) | — | −39.2 (−58.5 to −11.0)* | −31.1 (−50.6 to −5.7)* |
| Pets | ||||||
| Can f 1 ≥ 20 μg/g | 21.7 (−15.5 to 56.1) | −0.9 (−18.7 to 21.0) | −2.4 (−5.2 to 18.4) | 5.9 (−5.2 to 18.4) | −22.1 (−35.7 to −5.7)* | −12.1 (−25.1 to 3.1) |
| Fel d 1 ≥ 8 μg/g | — | — | −8.5 (−16.7 to 0.5) | — | — | — |
| Pests | ||||||
| Bla g 1 detectable | — | — | — | — | — | −30.5 (−52.6 to 1.6) |
| Mouse sighting | — | — | — | −10.8 (−19.3 to −1.4)* | — | — |
| SES | ||||||
| Black race/ethnicityb | −43.5 (−66.7 to −8.5)* | −6.4 (−32.5 to 29.8) | −12.1 (−25.1 to 3.2) | — | — | −22.9 (−40.5 to −0.2)* |
| Income < $35, 000/year | 83.5 (−11.2 to 287.8) | 27.0 (−21.2 to 104.7) | 3.1 (−11.6 to 20.2) | — | −27.4 (−45.9 to −2.5)* | — |
| Number/sex of children | ||||||
| Per boy | 15.9 (0.5 to 33.7)* | 12.5 (2.5 to 23.4)* | — | — | — | — |
| Per girl | — | — | — | −5.9 (−10.7 to −0.8)* | — | −8.2 (−14.8 to −0.9)* |
| Wall-to-wall carpet | — | −8.1 (−15.8 to 0.1) | — | — | — | — |
| Seasonc | ||||||
| Spring | −8.3 (−34.9 to 29.0) | −6.7 (−25.2 to 16.4) | 9.3 (−2.0 to 22.0) | 3.8 (−8.2 to 17.4) | 0.9 (−18.5 to 24.8) | 1.2 (−15.3 to 20.9) |
| Summer | −13.3 (−37.2 to 19.8) | −10.3 (−27.2 to 10.6) | 21.8 (9.7 to 35.3)* | −10.6 (−20.5 to 0.5) | 16.5 (−5.1 to 43.1) | 24.1 (4.8 to 46.8)* |
| Autumn | 1.1 (−33.0 to 52.7) | −15.2 (−35.1 to 10.7) | −1.9 (−14.0 to 12.0) | −0.6 (−14.4 to 15.4) | 13.2 (−12.3 to 46.0) | 16.5 (−5.9 to 44.2) |
| Model adjusted R2 | 8.3 | 4.9 | 6.9 | 4.9 | 4.6 | 6.0 |
| Multiple regression models with questionnaire and allergen (pest/pet) predictors | ||||||
| Dampness | ||||||
| Water/mold | 61.3 (22.8 to 111.7)* | 42.5 (19.4 to 70.0)* | — | 5.1 (−4.8 to 16.1) | 18.0 (−0.7 to 40.3) | 12.5 (−2.4 to 29.7) |
| Central air | −26.4 (−44.3 to −2.7)* | −15.7 (−29.7 to 1.0) | — | −13.8 (−22.2 to −4.4)* | — | — |
| Apartment | 10.0 (−41.4 to 106.4) | −14.7 (−43.3 to 28.4) | −15.3 (−30.6 to 3.4) | — | −38.1 (−57.5 to −9.3)* | −29.1 (−48.6 to −2.3)* |
| Pets | ||||||
| Dog ownership | 23.5 (−9.7 to 68.7) | 7.2 (−12.5 to 31.3) | −8.0 (−16.7 to 1.5) | 10.9 (−1.0 to 24.2) | −19.1 (−33.5 to −1.6)* | −15.1 (−27.9 to 0.1) |
| Cat ownership | — | — | −8.2 (−16.9 to 1.4) | — | — | — |
| Pests | ||||||
| Cockroach sighting | — | — | — | — | — | −38.8 (−58.9 to −8.9)* |
| Mouse sighting | — | — | — | −10.8 (−19.3 to −1.4)* | — | — |
| SES | ||||||
| Black race/ethnicityb | −44.8 (−66.7 to −8.7)* | −5.9 (−32.1 to 30.4) | −11.6 (−24.7 to 3.7) | — | — | −24.0 (−41.2 to −1.9)* |
| Income < $35, 000/year | 85.4 (−11.2 to 287.0) | 26.3 (−21.5 to 103.8) | 2.6 (−12.0 to 19.6) | — | −27.4 (−46.0 to −2.4)* | — |
| Number/sex of children | ||||||
| Per boy | 16.3 (0.8 to 34.1)* | 13.0 (3.1 to 24.0)* | — | — | — | — |
| Per girl | — | — | — | −6.0 (−10.8 to −0.9)* | — | −8.7 (−15.3 to −1.5)* |
| Wall-to-wall carpet | — | −7.9 (−15.6 to 0.5) | — | — | — | — |
| Seasonc | ||||||
| Spring | 1.5 (−32.7 to 53.1) | −6.4 (−25.0 to 16.9) | 9.0 (−2.3 to 21.6) | 4.5 (−7.6 to 18.1) | −0.3 (−19.5 to 23.5) | 1.2 (−17.2 to 18.1) |
| Summer | −13.8 (−37.6 to 19.0) | −10.3 (−27.6 to 10.1) | 22.6 (10.4 to 36.2)* | −10.9 (−20.7 to 0.2) | 16.6 (−5.2 to 43.3) | 22.5 (3.5 to 44.9)* |
| Autumn | −7.3 (−34.0 to 30.5) | −15.0 (−34.9 to 11.0) | −1.5 (−13.7 to 12.3) | −0.3 (−14.1 to 15.7) | 13.4 (−12.2 to 46.4) | 13.8 (−8.0 to 40.8) |
| Model adjusted R2 | 5.8 | 7.8 | 7.5 | 5.5 | 6.5 | 6.9 |
a
Absence of the home characteristic served as the reference category for each predictor unless otherwise noted. Dashes indicate that the characteristic was not entered into the model.
b
Reference category is all other race/ethnicity classifications (white, Hispanic, Asian, and other).
c
Reference category is winter.
*
p < 0.05.