Table 3.
Adjusteda linear regression coefficients for change in semen quality or sperm measures associated with a ln-unit increase in urinary concentrations of MP or PP (n = 190).
| MP |
PP |
|||
|---|---|---|---|---|
| Semen/sperm measure | β-Coefficient (95% CI) | p-Value | β-Coefficient (95% CI) | p-Value |
| Semen quality | ||||
| Total count (106)b | −0.07 (−0.25 to 0.11) | 0.42 | −0.05 (−0.17 to 0.08) | 0.45 |
| Concentration (106/mL)b | −0.08 (−0.24 to 0.08) | 0.33 | −0.06 (−0.17 to 0.05) | 0.27 |
| Motility (% motile) | −0.48 (−3.26 to 2.30) | 0.73 | −0.20 (−2.09 to 1.69) | 0.84 |
| Morphology (% normal) | 0.04 (−0.52 to 0.60) | 0.89 | 0.14 (−0.24 to 0.52) | 0.46 |
| Sperm motion | ||||
| VSL (μm/sec) | 0.001 (−1.72 to 1.73) | 1.00 | −0.05 (−1.22 to 1.12) | 0.93 |
| VCL (μm/sec) | −0.17 (−3.09 to 2.75) | 0.91 | −0.18 (−2.17 to 1.80) | 0.86 |
| Linearity (%) | −0.25 (−2.00 to 1.50) | 0.78 | 0.002 (−1.19 to 1.19) | 1.00 |
| DNA damagec | ||||
| Comet extent (μm) | 0.67 (−6.10 to 7.45) | 0.84 | −1.19 (−5.61 to 3.22) | 0.59 |
| TDM (μm) | −1.31 (−3.58 to 0.95) | 0.25 | −1.42 (−2.88 to 0.04) | 0.06 |
| Tail% | 2.35 (−0.16 to 4.85) | 0.07 | 0.67 (−0.98 to 2.32) | 0.42 |
CI, confidence interval.
a
Adjusted for SG, age, BMI, abstinence period, current smoking, and time of day of urine/semen sample collection.
b
Model included ln-transformations of parabens, sperm count, and sperm concentration.
c
n = 132.