Skip to main content
. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: RNA Biol. 2010 May–Jun;7(3):373–380. doi: 10.4161/rna.7.3.11693

Figure 6.

Figure 6

The putative miR-107 targets identified experimentally by RIP-Chip were subjected to biochemical validation. These proteins are GRN, INSIG1 and PPIB, which are targeted by miR-107 in the open reading frame as shown in Figure 5. Immunoblot analyses of these proteins’ expression following transfections of miR-107 (versus control miRNA) show that the expression of these genes are effectively suppressed by miR-107. Beta-Actin immunoblots following identical transfections provides a negative control.