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. 2011 Feb 17;7(2):e1001308. doi: 10.1371/journal.pgen.1001308

Table 4. SNPs with strongest evidence for association under each analysis condition.

SNP Group p-value Chra Position (bp) Alleleb Freq-control Freq-case ORc Genes
rs2075650 CCall 2.95×10−81 19 50087459 A 0.820 0.615 0.35 APOE, APOC1, APOC4 TOMM40, PVRL2
rs2075650 Ethnic stratified 1.18×10−15 19 50087459 A APOE, APOC1, APOC4 TOMM40, PVRL2
rs2075650 AJ 3.74×10−8 19 50087459 A 0.875 0.639 0.25 APOE, APOC1, APOC4 TOMM40, PVRL2
rs2075650 NW 3.21×10−73 19 50087459 A 0.814 0.608 0.35 APOE, APOC1, APOC4 TOMM40, PVRL2
rs7007878 SE 6.53×10−6 8 29098372 A 0.446 0.755 3.83 KIF13B
rs10489216 APOE ε3ε2+ε2ε2 8.44×10−7 1 166869486 G 0.780 0.5 0.28 DPT, XCL1
rs7814569 APOE ε3ε3 1.18×10−6 8 81252421 A 0.930 0.871 0.51 ZBTB10, TPD52
rs4145454 APOE ε4ε3 1.03×10−6 6 164492026 G 0.706 0.786 1.53
rs201119 APOE ε4ε4 1.52×10−8 10 11089983 A 0.793 0.939 4.02 CUGBP2, PITRM1
rs2673604 APOE stratified 2.60×10−6 8 133480789 A KCNQ3
a

Chromosome.

b

Allele depicted is the allele on the Illumina TOP strand.

c

Odds ratio with respect to allele noted.