Table 4. SNPs with strongest evidence for association under each analysis condition.
SNP | Group | p-value | Chra | Position (bp) | Alleleb | Freq-control | Freq-case | ORc | Genes |
rs2075650 | CCall | 2.95×10−81 | 19 | 50087459 | A | 0.820 | 0.615 | 0.35 | APOE, APOC1, APOC4 TOMM40, PVRL2 |
rs2075650 | Ethnic stratified | 1.18×10−15 | 19 | 50087459 | A | APOE, APOC1, APOC4 TOMM40, PVRL2 | |||
rs2075650 | AJ | 3.74×10−8 | 19 | 50087459 | A | 0.875 | 0.639 | 0.25 | APOE, APOC1, APOC4 TOMM40, PVRL2 |
rs2075650 | NW | 3.21×10−73 | 19 | 50087459 | A | 0.814 | 0.608 | 0.35 | APOE, APOC1, APOC4 TOMM40, PVRL2 |
rs7007878 | SE | 6.53×10−6 | 8 | 29098372 | A | 0.446 | 0.755 | 3.83 | KIF13B |
rs10489216 | APOE ε3ε2+ε2ε2 | 8.44×10−7 | 1 | 166869486 | G | 0.780 | 0.5 | 0.28 | DPT, XCL1 |
rs7814569 | APOE ε3ε3 | 1.18×10−6 | 8 | 81252421 | A | 0.930 | 0.871 | 0.51 | ZBTB10, TPD52 |
rs4145454 | APOE ε4ε3 | 1.03×10−6 | 6 | 164492026 | G | 0.706 | 0.786 | 1.53 | |
rs201119 | APOE ε4ε4 | 1.52×10−8 | 10 | 11089983 | A | 0.793 | 0.939 | 4.02 | CUGBP2, PITRM1 |
rs2673604 | APOE stratified | 2.60×10−6 | 8 | 133480789 | A | KCNQ3 |
Chromosome.
Allele depicted is the allele on the Illumina TOP strand.
Odds ratio with respect to allele noted.