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. 2011 Feb 17;7(2):e1001314. doi: 10.1371/journal.pgen.1001314

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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(A) A heatmap representation of BLASTN comparison of rodent-specific genes against sequenced L. reuteri genomes. Genes whose distribution throughout the species L. reuteri was determined by PCR are marked by arrows. (B) Distribution of host-specific genes throughout the phylogenetic spectrum of L. reuteri. A maximum likelihood tree of MLSA data from 116 L. reuteri strains is shown [20], and the strains for which genome sequences were included are marked by arrows. Pie charts showing the proportion of queried strains within lineages possessing the targeted genes (ureC, urease; Lr_70892, secA2, surface proteins Lr_70131, Lr_70581, Lr_70697, and pduC of the pdu-cbi-cob-hem cluster) as detected by PCR.