Table 1.
Characteristics of lung cancer cases and controls
| Characteristic | Cases (n = 626) n (%) |
Controls (n = 626) n (%) |
Pa |
|---|---|---|---|
| Sex | |||
| Male | 541 (86.4) | 541 (86.4) | |
| Female | 85 (13.6) | 85 (13.6) | 1.000 |
| Age (yrs), mean (SD) | 64.48 (10.96) | 63.61 (11.21) | 0.161 |
| median (IQR) | 65.00 (17.00) | 64.00 (18.00) | 0.172 |
| Hospital areab | |||
| Gijon (Cabueñes Hospital) | 355 (56.7) | 355 (56.7) | |
| Aviles (San Agustin Hospital) | 176 (28.1) | 176 (28.1) | |
| Oviedo (General Hospital) | 58 (9.3) | 58 (9.3) | |
| Mieres (Alvarez-Buylla Hospital) | 37 (5.9) | 37 (5.9) | 1.000 |
| Smoking Status | |||
| Never | 47 (7.5) | 182 (29.1) | |
| Ever | 579 (92.5) | 444 (70.9) | <0.001 |
| Former | 181 (31.3) | 227 (51.1) | |
| Current | 398 (68.7) | 217 (48.9) | <0.001 |
| PYc, mean (SD) | 62.01 (35.34) | 38.27 (31.96) | <0.001 |
| median (IQR) | 55.00 (40.75) | 32.00 (35.86) | <0.001 |
| Smoking | |||
| Never | 47 (7.6) | 182 (29.6) | |
| Former < 38 PY | 62 (10.0) | 151 (24.6) | |
| Current < 38 PY | 72 (11.7) | 102 (16.6) | |
| Former ≥ 38 PY | 117 (18.9) | 70 (11.4) | |
| Current ≥ 38 PY | 320 (51.8) | 109 (17.8) | <0.001 |
| Family history of cancer | |||
| None | 338 (56.2) | 371 (59.8) | |
| Other cancers | 190 (31.6) | 204 (32.9) | |
| Lung cancer | 73 (12.2) | 45 (7.3) | 0.015 |
| Histologic type | |||
| Squamous cell carcinoma | 242 (39.4) | ||
| Adenocarcinoma | 182 (29.6) | ||
| Small cell carcinoma | 109 (17.7) | ||
| Large cell carcinoma | 18 (2.9) | ||
| Non-differentiated | 42 (6.8) | ||
| Others | 14 (2.3) | ||
| Clinical diagnosis | 8 (1.3) | ||
| Missing | 11 | ||
| Worker in high-risk occupation | |||
| Never | 220 (35.4) | 245 (39.3) | |
| Ever | 401 (64.6) | 379 (60.7) | 0.162 |
| Time in high-risk occupationd, mean (SD) | 26.31 (14.59) | 24.24 (13.95) | 0.045 |
| Median (IQR) | 29.00 (25.00) | 26.00 (23.00) | 0.036 |
| Population living in their last-residence | |||
| for more than 5 years | 547 (88.90) | 552 (89.30) | 0.903 |
| for more than 10 years | 492 (80.00) | 495 (80.10) | 0.977 |
aTwo-sided χ2 test, and Mann-Whitney test where appropriate
bHospital area refers to each hospital's health catchment area
cPack-years for ever-smokers
dTime (in years) for ever-workers