Table 4.
Odds ratios of lung cancer, overall and by histologic subtype, in Asturias' two main hospital catchment areas, by exposure category
| Total | Squamous cell carcinoma | Adenocarcinoma | Small cell carcinoma | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Controls | Cases | OR (95%CI)a | P-valueb | Cases | OR (95%CI)a | P-valueb | Cases | OR (95%CI)a | P-valueb | Cases | OR (95%CI)a | P-valueb | |
| N | N | N | N | N | |||||||||
| Gijon | |||||||||||||
| Unexposed | 248 | 211 | Reference | 80 | Reference | 75 | Reference | 36 | Reference | ||||
| Industrial | 36 | 41 | 1.51 (0.85-2.66) | 15 | 1.57 (0.73-3.39) | 13 | 1.01 (0.46-2.21) | 10 | 2.17 (0.86-5.46) | ||||
| Urban | 36 | 55 | 2.17 (1.25-3.76) | 22 | 3.07 (1.42-6.60) | 19 | 2.01 (1.00-4.05) | 6 | 1.51 (0.52-4.37) | ||||
| Semi-urban | 35 | 48 | 1.66 (0.94-2.92) | 0.017 | 19 | 1.91 (0.90-4.03) | 0.018 | 16 | 1.53 (0.72-3.22) | 0.218 | 10 | 2.01 (0.81-5.03) | 0.237 |
| Aviles | |||||||||||||
| Unexposed | 122 | 126 | Reference | 51 | Reference | 25 | Reference | 25 | Reference | ||||
| Industrial | 18 | 28 | 0.96 (0.45-2.06) | 6 | 0.50 (0.16-1.58) | 11 | 2.12 (0.80-5.65) | 6 | 0.85 (0.25-2.86) | ||||
| Urban | 18 | 13 | 0.95 (0.38-2.34) | 6 | 0.88 (0.26-3.03) | 6 | 1.70 (0.50-5.79) | 0 | - | ||||
| Semi-urban | 18 | 9 | 0.56 (0.22-1.45) | 0.693 | 1 | 0.19 (0.02-1.60) | 0.214 | 3 | 1.05 (0.25-4.33) | 0.453 | 2 | 0.63 (0.11-3.69) | 0.238 |
aORs were estimated from a multiple logistic regression model that included age, sex, tobacco consumption, family history of cancer, and occupation
bP-value for the whole effect of outdoor exposure