Table 1.
List of proteins that were down-regulated in the lesion center at day 14 after SCI compared to 1 day after SCI.
| Spot no. |
Function | Protein name | Protein ID | Expression (14d/1d) |
14d_mean (SEM) |
1d_mean (SEM) |
p value | Mw/pI | Score | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1~3 | acute-phase response | Serotransferrin | TRFE | down | 1.241 (0.394) |
3.097 (0.627) |
0.035 | 78512/7.14 | 186 | |
| 121 | chaperone | Stress-70 protein, mitochondrial | GRP75 | down | 0.109 (0.032) |
0.608 (0.132) |
0.008 | 74097/5.97 | 64 | |
| 102 | metabolism | Carbonic anhydrase 1 | CAH1 | down | ND | 0.212 (0.084) |
NA | 28282/6.86 | 68 | |
| 41, 42, 97 | metabolism | Fructose-bisphosphate aldolase C | ALDOC | down | 0.440 (0.047) |
1.283 (0.263) |
0.009 | 39658/6.67 | 187 | |
| 96 | oxidoreduction | Sorbitol dehydrogenase | DHSO | down | ND | 0.079 (0.056) |
NA | 38780/7.14 | 66 | |
| 77 | stress response | Heat shock 70 kDa protein 4 | HSP74 | down | ND | 0.193 (0.087) |
NA | 93997/5.13 | 127 | |
| 78 | transport | Hemopexin | HEMO | down | 0.360 (0.142) |
0.997 (0.123) |
0.023 | 52060/7.58 | 139 |
The proteins changed at least 1.5-fold were listed above. The proteins were downregulated with a p value < 0.05. NA, not applicable; ND, non-detectable.