Table 2.
List of proteins that were up-regulated in the lesion center at day 14 after SCI compared to 1 day after SCI.
| Spot no. |
Function | Protein name | Protein ID | Expression (14d/1d) |
14d_mean (SEM) |
1d_mean (SEM) |
p value | Mw/pI | Score |
|---|---|---|---|---|---|---|---|---|---|
| 35 | actin filament capping | Macrophage-capping protein, Actin regulatory protein CAP-G | CAPG | up | 0.239 (0.080) |
0.022 (0.021) |
0.050 | 39060/6.11 | 95 |
| 52 | actin filament capping | F-actin-capping protein subunit beta | CAPZB | up | 0.194 (0.041) |
0.025 (0.025) |
0.013 | 30952/5.69 | 67 |
| 110 | acute inflammatory response | Haptoglobin | HPT | up | 0.132 (0.028) |
ND | NA | 39052/6.10 | 63 |
| 58,59 | cell differentiation | Galectin-3 | LEG3 | up | 0.422 (0.091) |
ND | NA | 27241/8.59 | 99 |
| 33 | cytoskeleton | Beta-actin | ACTB | up | 4.016 (0.641) |
1.630 (0.260) |
0.017 | 42052/5.29 | 139 |
| 61 | GTPase activation | Rho GDP-dissociation inhibitor 1 | GDIR1 | up | 0.486 (0.248) |
ND | NA | 23450/5.12 | 106 |
| 60 | metabolism | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | UCHL1 | up | 1.106 (0.179) |
0.393 (0.096) |
0.014 | 25165/5.14 | 83 |
| 22 | microtubule | Tubulin beta-5 chain | TBB5 | up | 0.763 (0.249) |
ND | NA | 50095/4.78 | 83 |
| 69 | oxidoreduction | Flavin reductase | BLVRB | up | 0.078 (0.025) |
ND | NA | 22297/6.49 | 93 |
| 66 | oxidoreduction | Heat shock protein beta-1 | HSPB1 | up | 0.201 (0.024) |
0.025 (0.002) |
0.010 | 22936/6.12 | 102 |
| 74 | oxidoreduction | Superoxide dismutase [Mn], mitochondrial | SODM | up | 0.300 (0.045) |
0.105 (0.029) |
0.020 | 24887/8.96 | 64 |
| 54 | protease inhibitor | Latexin, Endogenous carboxypeptidase inhibitor | LXN | up | 0.118 (0.020) |
ND | NA | 25735/5.77 | 68 |
The proteins changed at least 1.5-fold were listed above. The proteins were upregulated with a p value < 0.05. NA, not applicable; ND, non-detectable.