Table 3.
Cytokine levels (in pg/ml, median and range) without antigenic stimulus and after stimulation with BCG and PHA in the supernatant from mothers' peripheral mononuclear cell cultures collected at 35 weeks of gestation
| HIV-uninfected controls | HIV+ mothers | p value | |
|---|---|---|---|
| IL-2 non-stimulated | 0.0 (0 -76) | 0.0 (0 - 767) | 0.47 |
| BCG | 0.0 (0 - 78) | 2.14 (0 - 232) | 0.44 |
| PHA | 89.8 (0 -968) | 24.5 (0 - 1421) | 0.34 |
| IL-4 non-stimulated | 41.0 (38 - 278) | 22.2 (9.2 - 76) | <0.005 |
| BCG | 39.1 (37 - 216) | 22.8 (9.5 - 76) | <0.005 |
| PHA | 52.0 (39 - 146) | 30.14 (14 - 419) | <0.005 |
| IL-7 non-stimulated | 67.0 (0 -88) | 0.0 (0 - 90) | 0.05 |
| BCG | 66.0 (0 - 89) | 0.0 (0 - 86) | 0.04 |
| PHA | 66.0 (0 - 85) | 0.0 (0 - 87) | 0.03 |
| IL-10 non-stimulated | 0.0 (0 - 490) | 17 (0 - 18015) | 0.14 |
| BCG | 736 (0 - 4910) | 764 (0 - 43384) | 0.49 |
| PHA | 498 (0 - 2925) | 405 (0 - 58344) | 0.56 |
| IL-12 non-stimulated | 0.51 (0 - 2.83) | 0.51 (0 -2.4) | 0.62 |
| BCG | 1.18 (1 - 31) | 1.0 (0 - 11) | 0.27 |
| PHA | 1.34 (0 - 51) | 1.53 (0 - 33) | 0.68 |
| IFNγ non-stimulated | 0.0 (0 - 94) | 13.2 (0 - 131) | 0.73 |
| BCG | 2.73 (0 - 1343) | 29.2 (0 - 999) | 0.42 |
| PHA | 110.2 (0 - 2528) | 308.9 (0 - 5143) | 0.16 |
| TNFα non-stimulated | 245.4 (0 - 4826) | 526.8 (0 - 7928) | <0.0005 |
| BCG | 5374.0 (0 - 13852) | 2072.7 (86 - 34130) | 0.83 |
| PHA | 827.6 (261 - 20889) | 1513.3 (244 - 14448) | 0.22 |