Table 6.
B lymphocyte subsets and B-cell maturation in cord blood studied in the CD45/CD34/CD19/CD22 and sIgM/CD34/CD19/CD10 combinations (median and range)
| Non exposed controls | HIV exposed | HIV exposed drug using mother | p value | |
|---|---|---|---|---|
| % CD19+ | 3.6 | 5.2 | 7.0 | 0.01 |
| % CD19+CD5+ * | 59.5 | 77.8 | 67.6 | 0.007 |
| % CD45lowCD34+CD19+CD22-/+ ** | 0.73 | 0.42 | 1.1 | |
| (0.2 - 3.13) | (0.07 - 1.22) | (0.78 - 1.4) | 0.01 | |
| % CD45-/+CD34lowCD19+CD22+ *** | 2.62 | 2.94 | 13.0 | |
| (0.24 - 6.8) | (1.5 - 8.2) | (8.8-19.4) | 0.01 | |
| % CD45+CD34-CD19+CD22+ **** | 96.7 | 96.7 | 86.3 | |
| (91 - 99) | (91.6 - 98.4) | (79 - 90) | 0.02 | |
| %sIgM-CD34+CD19+CD10-/+ ** | 0.4 | 0.2 | 1.5 | |
| (0.10-2.2) | (0.05-0.95) | (0.4-2.7) | 0.05 | |
| %sIgM+CD34-/+CD19+CD10-/+ *** | 2.4 | 2.2 | 6.5 | |
| (0.87-7.1) | (0.6-4.5) | (2.1-71) | 0.13 | |
| %sIgM+CD34-CD19+CD10-/+ **** | 97.1 | 97.3 | 92.5 | |
| (91.3-98.9) | (94.6-99.3) | (92.0-95.0) | 0.05 |
* percentage of the total CD19+ cells, ** immature cells, ***intermediary and ****mature B-cells