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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Neurotoxicol Teratol. 2010 Sep 22;33(2):240–243. doi: 10.1016/j.ntt.2010.09.003

Table 3.

Fetal cardiac and movement parameter comparisons by treatment group

Methadone Buprenorphine z
M(SD) M(SD)
24/28 weeks n = 8 n = 4
 Fetal heart rate (bpm) 139.11(5.51) 136.10(7.77) −0.85
 Fetal heart rate variability 3.69(1.01) 5.05(1.04) −2.06*
 Accelerations 0(0) 1.25(1.89) −2.09*
 Motor activity 4.80(1.45) 5.95(.79) −1.36
 Movement duration 16.07(4.72) 27.46(14.91) −1.87^
 FHR-FM coupling(%) 7.64(6.49) 18.78(9.26) −2.04*
32/36 weeks n = 6 n=5
Fetal heart rate (bpm) 133.42(7.89) 134.58(7.12) −0.18
Fetal heart rate variability 4.43(0.78) 5.30(2.16) −0.37
Accelerations 1.17(1.17) 2.80(3.83) 0
Motor activity 3.58(1.18) 5.92(2.95) −2.01*
Movement duration 8.74 (2.71) 21.53 (13.22) −2.01*
FHR-FM coupling(%) 27.42(13.97) 18.88(6.90) −1.10
^

p < .10.

*

p < .05.