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Dissociation constant (K d) of compounds for XcOGT-WT from SPR experiments
| Compound | K d (mM) | |
|---|---|---|
| WT-XcOGT | D471A-XcOGT | |
| UDP | 0.110 ± 0.001 | n.b. |
| C-UDP | 0.530 ± 0.006 | n.b. |
| UDP-GlcNAc | 15.1 ± 0.5 | n.b. |
| UDP-S-GlcNAc | >1 | >1 |
| UDP-C-GlcNAc | >1 | >1 |
| Alloxan | >1 | n.d. |
n.b. = no binding
n.d. = not determined
