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. 2011 Feb;119(2):111–118. doi: 10.1111/j.1600-0463.2010.02700.x

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Fig. 2 — Histopathology in pigs inoculated intra-arterially (a. brachialis dextra) with 50 000 CFU/kg BW. (A) Radius: a microabscess located deep in the metaphyseal area, H&E. (B) Metacarpale III: colonies of bacteria (→) are present at the junction between the growth plate (GP) and the metaphysis (MP) and the epiphysis (EP), H&E. (C) Epiphysis of phalanx proximalis III: multiple Staphylococcus aureus bacteria are seen centrally in the microabscess. Surrounding cells are arranged in a pattern of palisades. Immunostaining for S. aureus. (D) The centre of the microabscesses was made up by accumulation of neutrophils, H&E. (E) Within the blood vessels of the growth plate (GP), fibrin deposition was sometimes observed (→), phosphotungstic acid haematoxylin (PTAH). (F) Osteonecrosis (→) was often present just beneath the growth plate together with areas of necrotic bone marrow cells (), H&E. (G) Trabeculae with empty lacunae () were typically surrounded by bone resorbing osteoclasts (→), H&E. (H) Multiple S. aureus bacteria were often identified in connection with the capillary loops at the junction between the growth plate (GP) and the metaphysis (MP). Immunostaining for S. aureus.

Inline graphic — Histopathology in pigs inoculated intra-arterially (a. brachialis dextra) with 50 000 CFU/kg BW. (A) Radius: a microabscess located deep in the metaphyseal area, H&E. (B) Metacarpale III: colonies of bacteria (→) are present at the junction between the growth plate (GP) and the metaphysis (MP) and the epiphysis (EP), H&E. (C) Epiphysis of phalanx proximalis III: multiple Staphylococcus aureus bacteria are seen centrally in the microabscess. Surrounding cells are arranged in a pattern of palisades. Immunostaining for S. aureus. (D) The centre of the microabscesses was made up by accumulation of neutrophils, H&E. (E) Within the blood vessels of the growth plate (GP), fibrin deposition was sometimes observed (→), phosphotungstic acid haematoxylin (PTAH). (F) Osteonecrosis (→) was often present just beneath the growth plate together with areas of necrotic bone marrow cells (), H&E. (G) Trabeculae with empty lacunae () were typically surrounded by bone resorbing osteoclasts (→), H&E. (H) Multiple S. aureus bacteria were often identified in connection with the capillary loops at the junction between the growth plate (GP) and the metaphysis (MP). Immunostaining for S. aureus.