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Mcl-1 overexpression in tumor cells reduces cell death induced by ABT-737 and actinomycin D. Panc-1 cells (A) or A549 cells (B) overexpressing Mcl-1 and control cells were treated with the indicated amounts of ABT-737 and actinomycin D for 72 hours (Panc-1) or 48 hours (A549). Cell viability was determined by PI staining and data represent mean ± standard deviation of triplicate experiments. Experiments were performed independently three times.
