TABLE 3.
ANTIMICROBIAL ACTIVITY OF THE COMPOUNDS 7a-o
| Compd. | Zone of inhibition in mm | |||
|---|---|---|---|---|
| P. aeruginosa | S. aureus | Aspergillus niger | Curvularia lunata | |
| 7a | 17 | 17 | 17 | 18 |
| 7b | 15 | 16 | 14 | 15 |
| 7c | 15 | 15 | 16 | 17 |
| 7d | 17 | 16 | 15 | 17 |
| 7e | 16 | 16 | 16 | 15 |
| 7f | 17 | 15 | 16 | 16 |
| 7g | 15 | 16 | 16 | 17 |
| 7h | 16 | 17 | 19 | 18 |
| 7i | 19 | 19 | 18 | 18 |
| 7j | 17 | 16 | 18 | 17 |
| 7k | 19 | 18 | 18 | 19 |
| 7l | 20 | 19 | 19 | 18 |
| 7m | 19 | 18 | 19 | 18 |
| 7n | 18 | 20 | 19 | 19 |
| 7o | 19 | 18 | 20 | 19 |
| Standard | 24 | 26 | 24 | 22 |
| DMF | + ve | + ve | + ve | + ve |
Zone of inhibition expressed in mm. The Cup-plate method was followed and chloramphenicol and flucanazole were used as standards. The concentration of the drug used is 0.001 mol/ml in DMF