TABLE 7.
Comp. | Group | R1 | R2 | Volume of urine collected in ml after 5 h. | T/S (Lipschitz value) |
---|---|---|---|---|---|
Control | I | --- | ---- | 8 | 0.27 |
Frusemide | II | --- | ---- | 29 | 1.00 |
7a | III | H | H | 14 | 0.48 |
7b | IV | H | 4-OCH3 | 15 | 0.52 |
7c | V | H | 4-OH | 16 | 0.55 |
7d | VI | H | 4-Cl | 15 | 0.52 |
7e | VII | H | 4-NO2 | 19 | 0.65 |
Control, concentration of drug used is 30 mg/kg in Tween-80 (0.1%, 5 ml) solution. Number of animals in each group 6