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. 2008 Nov-Dec;70(6):768–775. doi: 10.4103/0250-474X.49119

TABLE 3.

STABILITY OF OPTIMIZED ACECLOFENAC PROLIPOSOMES FORMULATION (DRUG:LECITHIN, 0.1:2.0)

Time Temperature Residual drug content Entrapment

(mo) efficiency (%, mean±SD, n=3) (%, mean±SD, n=3)
0 RT 100 100
1 98.33±1.6% 98.93±1.4%
2 96.60±1.8% 97.02±1.6%
3 95.83±1.5% 96.37±1.8%
1 RT 95.82±1.9% 94.27±1.5%
2 RT 94.92±1.6% 90.00±1.8%
3 RT 93.33±2.1% 85.61±2.5%
1 40° 87.50±2.2% 92.59±1.6%
2 40° 85.79±2.5% 77.89±2.4%
3 40° 81.61±2.7% 72.51±1.8%

SD denotes standard deviation