Skip to main content
. 2009 Feb 27;1(1):83–96.

Figure 5.

Figure 5

Nodal and ALK7-ca induced apoptosis. A) DNA fragmentation assays. MDA-MB-231 and MCF-7 cells were transfected with control vector (EV), Nodal (N) and ALK7-ca (CA) and 48h later, DNA extracted and analyzed. B) TUNEL assays. Cells were transfected as in A and apoptotic cells were identified by TUNEL staining. C) Western blot analysis of Bcl2, Bcl-XL, and active caspase 3. Bcl2 and Bcl-XL levels were determined at 24h after transfection whereas active caspase 3 was measured at 48h after transfection.