Fig. (4).

Inhibition of NGF-induced neurite outgrowth by Src-family kinase inhibitor SU6656. NS-1 cells were treated with varying doses of SU6656, and then NGF was added to a final concentration of 20ng/ml. Neurite outgrowth was analyzed at 48h by HCMR. The curve was fitted in GraphPad PRISM using a 4-parameter logistic model with recursive least squares weighting. Each point represents an average of three experiments in triplicate. The bars represent the standard deviation of the data from the means.