Table 4.
Active Potentiators of NGF-Induced Neurite Outgrowth Identified from Prestwick Compound Set
| Name | Structure | Formula | Molecular weight | Classification/ function |
|---|---|---|---|---|
| Isoflupredone acetate |  |
C23H29FO6 | 420.5 | Anti-inflammatory sterol |
| Fludrocortisone acetate |  |
C23H31FO6 | 422.5 | Aldosterone analog |
| Thioguanosine |  |
C10H13N5O4S | 299.3 | Purine antagonist cell stressor used in the treatment of acute nonlymphocytic leukemias |
| Etoposide |  |
C29H32O13 | 588.6 | Topoisomerase II inhibitor shown to promote neurite outgrowtha |
| Gibberellic acid |  |
C19H22O6 | 346.4 | Growth-inducing Plant hormoneb |
| Oxyphen-butazone |  |
C19H20N2O3 | 324.4 | NSAID with multiple molecular targets |
NSAID: non-steroid anti-inflammatory.
a
(Aoki et al., 2003).TJ
b
(Halliday and Fankhauser, 2003).