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. Author manuscript; available in PMC: 2011 Feb 18.
Published in final edited form as: Mol Cancer Ther. 2010 Jan 6;9(1):202–210. doi: 10.1158/1535-7163.MCT-09-0771

Figure 1. Withaferin-A inhibits Notch signaling in colon cancer cells.

Figure 1

HCT-116, SW-480, and SW-620 cells were treated with either vehicle control (DMSO) or WA for varying time intervals. Cell lysates were subjected to western blot analysis using (A) Notch-1 (cleaved), Hey-1 and Hes-1 antibodies, and (B) gamma-secretase components. GAPDH was used as the internal loading control.