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. 2011 Jan 31;108(7):3047–3052. doi: 10.1073/pnas.1010529108

Fig. 4.

Fig. 4.

GF mice show altered expression of anxiety and synaptic plasticity-related genes. (A) Representative autoradiograms showing NGFI-A mRNA expression at the level of the frontal cortex of SPF and GF mice (OFC, orbital frontal cortex; AO, anterior olfactory region). (A') Bars show expression of NGFI-A mRNA (nCi/g) in the OFC and AO of SPF and GF mice. (B) Representative autoradiograms showing BDNF mRNA expression at the level of amygdala and dorsal hippocampus of SPF and GF mice (BLA, basolateral amygdala; CA1, CA1 region of the dorsal hippocampus). (B') Bars show expression of BDNF mRNA (nCi/g) in the BLA and CA1 region of SPF and GF mice. (C) Representative autoradiograms showing dopamine D1 receptor (Drd1a) mRNA expression at the level of the striatum and nucleus accumbens of SPF and GF mice (STR, striatum; Accb, nucleus accumbens, shell region). (C') Bars show expression of Drd1a mRNA (nCi/g) in the STR and Accb of SPF and GF mice. (D) Representative autoradiograms showing Drd1a mRNA expression at the level of the dorsal hippocampus of SPF and GF mice (DG, dentate gyrus; PtCx, parietal cortex, somatosensory area). (D') Bars show expression of Drd1a mRNA (nCi/g) in the DG and PtCx of SPF and GF mice. All data (A'–D') are expressed as means ± SEM, n = 8 per group. Filled bars represent GF mice. Open bars represent SPF mice. *P < 0.05, *P < 0.001 compared with SPF mice.