Table 1.
Expression of synaptophysin and PSD-95 in various brain regions of GF, SPF, and CON mice
Frontal cortex |
Striatum |
Hippocampus |
||||
Mice | Synaptophysin | PSD-95 | Synaptophysin | PSD-95 | Synaptophysin | PSD-95 |
GF | 0.989 ± 0.058 | 1.039 ± 0.085 | 1.803 ± 0.037* | 2.171 ± 0.042* | 0.982 ± 0.046 | 1.025 ± 0.136 |
SPF | 1.000 ± 0.062 | 1.000 ± 0.145 | 1.000 ± 0.015* | 1.000 ± 0.036* | 1.000 ± 0.051 | 1.000 ± 0.075 |
CON | 0.992 ± 0.022 | 1.011 ± 0.090 | 1.013 ± 0.028* | 1.001 ± 0.063* | 0.973 ± 0.039 | 1.045 ± 0.076 |
Expression of synaptophysin and PSD-95 in the frontal cortex, striatum, and hippocampus of GF (n = 4), SPF (n = 4), and CON (n = 6) mice were quantified and calculated against their respective actin expression (Fig. 6). The values were then compared against the SPF mice values and expressed as average fold increase. Values are expressed as means ± SEM.
*P < 0.05 compared with SPF mice.