Table 2.

Effect of MNR on glial and neuronal maturation

Protein expression (area of IR, mm2 × 10−2)	Controls	MNR
GFAP
SVZ	2.47 ± 0.97	1.79 ± 0.43
Intermediate zone	3.20 ± 0.84	3.22 ± 0.53
Cortical plate	0.84 ± 0.41	0.77 ± 0.20
Vimentin
SVZ	0.32 ± 0.08	0.33 ± 0.17
Intermediate zone	0.15 ± 0.07	0.13 ± 0.05
Cortical plate	0.24 ± 0.08	0.25 ± 0.05
S-100β
SVZ	1.97 ± 0.28	0.68 ± 0.39*
Intermediate zone	0.73 ± 0.17	0.91 ± 0.14
Cortical plate	1.04 ± 0.24	1.16 ± 0.54
O4
SVZ	0.29 ± 0.19	0.14 ± 0.09
Intermediate zone	0.19 ± 0.02	0.16 ± 0.02
Subplate/cortical plate	0.30 ± 0.04	0.21 ± 0.04*
NeuN
SVZ	0.01 ± 0.006	0.02 ± 0.014
Intermediate zone	0.39 ± 0.21	0.50 ± 0.34
Cortical plate	1.69 ± 1.22	1.69 ± 0.94
DCX
SVZ	2.32 ± 0.47	2.68 ± 0.52
Intermediate zone	0.66 ± 0.27	0.43 ± 0.08
Cortical plate	0.54 ± 0.31	0.99 ± 0.34
Golgi
Subplate	1.90 ± 0.33	1.23 ± 0.50*

*P < 0.05 in comparison to controls.