Table 2.

Independent associations with all-cause mortality and cumulative incidence of cardiovascular mortality in individuals with type 2 diabetes

All-cause mortality
Baseline parameter	Hazard ratio	P	95% CI
24-h urinary sodium excretion (per 100 mmol/day)	0.72	0.017	0.55–0.94
Age (per decade)	1.05	<0.001	1.03–1.07
Male sex (yes/no)	1.51	0.013	1.09–2.09
Pre-existing CVD (yes/no)	1.85	0.001	1.30–2.64
eGFR (per 10 mL/min/1.73 m2)	0.988	0.002	0.980–0.996
Atrial fibrillation (yes/no)	1.97	<0.001	1.39–2.81
Log10 AER	1.71	<0.001	1.38–2.12
Systolic blood pressure (mmHg)	0.986	0.015	0.974–0.997
Diabetes duration (decades)	1.02	0.010	1.01–1.04
Cardiovascular mortality
Baseline parameter	Sub-hazard ratio	P	95% CI
24-h urinary sodium excretion (per 100 mmol/day)	0.65	0.026	0.44–0.95
Male sex (yes/no)	1.93	0.011	1.17–3.20
Pre-existing CVD (yes/no)	1.88	0.014	1.14–3.11
eGFR (per 10 mL/min/1.73 m2)	0.985	0.001	0.98–0.99
Atrial fibrillation (yes/no)	2.78	<0.001	1.71–4.53
Log10 AER	1.76	<0.001	1.28–2.42
Systolic blood pressure (mmHg)	0.97	<0.001	0.96–0.99
Diabetes duration (decades)	1.05	<0.001	1.02–1.08

All-cause mortality: independent associations with all-cause mortality in individuals with type 2 diabetes in a multivariate Cox model. The model explained 52% of the variation in all-cause mortality (95% CI 0.42– 0.64) and was well specified (Harrell’s C: 0.79; PH test: P = 0.136; goodness-of-fit test: P ≥ 0.37). PH, proportional hazard. Cardiovascular mortality: independent associations with the cumulative incidence of cardiovascular mortality in individuals with type 2 diabetes in the Fine and Gray (proportional hazards) model after accounting for the competing risk of noncardiovascular death.