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. 2011 Feb;162(3):584–596. doi: 10.1111/j.1476-5381.2010.01063.x

Figure 4.

Figure 4

Effects of intra-ventrolateral periaqueductal gray microinjections of vehicle, cannabidiol (CBD) (3 nmol), cannabichromene (CBC) (6 nmol), OMDM-2 (3 nmol) and mustard oil (6 mol) on the tail flick induced RVM ON burst of firing (A). B shows the effect of vehicle, CBD (3 nmol) alone or CBD (3 nmol) in combination with AM251 (0.5 nmol), I-RTX (1 nmol), DPCPX (0.05 nmol), AP18 (6 nmol) or WAY100635 (0.34 nmol). C shows the effect of vehicle, CBC (6 nmol) alone or CBC (6 nmol) in combination with AM251 (0.5 nmol), I-RTX (1 nmol), DPCPX (0.05 nmol) and AP18 (6 nmol). Each histogram represents the mean ± SEM of 6–8 neurons. * indicates values significantly different (P < 0.05) from vehicle and ° from CBD (3 nmol) or CBC (6 nmol). DPCPX, 1,3-dipropyl-8-cyclopentylxanthine; I-RTX, 5′-iodo-resiniferatoxin.