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. 2011 Feb;162(3):722–732. doi: 10.1111/j.1476-5381.2010.01084.x

Figure 2.

Figure 2

(A) Comparison of transvalvular flow between groups. In untreated rabbits, AVv/LVOTv was 1.12 ± 0.04 (baseline) versus 1.17 ± 0.04 (8 weeks); and AVBS 4.7 ± 0.7 dB after 8 weeks. There was a statistically significant difference in the time-treatment interaction between the vitamin D2 (n = 14) and vitamin D2/ramipril (n = 16) groups [F = 5.6; P = 0.02; two-way analysis of variance (anova)]. (B) AVBS comparison between groups. Mean AVBS in the vitamin D2 alone group was higher compared with the vitamin D2/ramipril group (15.7 ± 1.8 dB vs. 9.9 ± 2.0 dB, respectively, P < 0.05; unpaired t-test). Mean AVBS for the untreated group was 4.7 ± 0.7 dB. (C) Interventricular septal dimension (IVSd) comparison between groups. Significant retardation of left ventricular hypertrophy as evident by a decrease in IVSd in the vitamin D2/ramipril treated group versus vitamin D2 treated alone over the 8 weeks of treatment was observed (F = 10.8, P < 0.01; two-way anova). AVBS, aortic valve backscatter score; AVv, aortic valve velocity; LVOTv, left ventricular outflow tract flow velocity.